Johnson, Sinclair, Huberman, Attia, Dorsey and more, on the record. The pills they share, what the research says, and the cheap version you can copy.
This in-depth guide covers everything you need to know about what supplements do billionaires take? the sourced list. Based on verified income data and real-world case studies from our database of 138 side hustle tactics.
Most billionaires have never said what pills they take. The handful who have, plus the longevity doctors and podcasters they listen to, keep landing on the same short list: vitamin D, omega-3 fish oil, magnesium, creatine and a multivitamin or greens powder, with NMN and resveratrol showing up in the more experimental stacks. The cheap basics on that list have the best evidence, and most of them cost a few dollars a month in store-brand form.
Below is every named person we could tie to a sourced public statement, what each one said, and then the supplements that show up most often, with what the research says and what they cost. Curious how far your own cupboard is from theirs?
Who said what: the roundup table
A rule before the table: each row comes from the person's own words (their site, podcast, book or a quote given to a reporter) or from a reputable outlet that reported it. Social media lists that say "Bezos takes X" with no source were left out. We searched for supplement statements from Jeff Bezos and Marc Benioff and found none in their own words, so they are absent from the table.
| Person | What they said they take | Source and date | Worth knowing |
|---|
| Bryan Johnson, Blueprint founder | Creatine (5 g on top of 2.5 g in his Longevity Mix), EPA/DHA 800 mg, collagen peptides, fiber powders, Blueprint capsules | His protocol page, current as of 2026 | He sells the products he lists. Full breakdown in our Bryan Johnson supplements list |
| David Sinclair, Harvard geneticist | NMN 1 g, resveratrol 1 g, cycling metformin and berberine, vitamin D3/K2, spermidine, glycine about 5 g, a baby aspirin most days | Reported by Peter Diamandis after a sit-down at the 2026 Abundance Summit (Metatrends, April 2026) | Metformin and aspirin are drugs. NMN gets its own post: NMN and NAD+ evidence |
| Peter Diamandis, entrepreneur and Metatrends writer | A stack of "over 60 supplements per day"; he says he mirrors "nearly 100%" of Sinclair's list, and adds creatine 5 g, CoQ10 with PQQ, urolithin A, NAC, magnesium glycinate and threonate | Metatrends, April 2026 | He lists peptides, including BPC-157 (see our BPC-157 guide), and a tirzepatide microdose separately |
| Andrew Huberman, Stanford neuroscientist and podcaster | AG1 greens powder "since 2012"; magnesium threonate, theanine, apigenin and inositol for sleep; 300 mg alpha GPC before cognitive work or workouts | Huberman Lab episode, January 9, 2023 | Also wrote that 3 to 4 nights a week he adds 2 g glycine and 100 mg GABA (newsletter, September 2021) |
| Peter Attia, longevity physician | Vitamin D about 5,000 IU, high-EPA fish oil (four capsules, about 2 g EPA), magnesium in three forms aiming for about 1 g elemental, B6, methylfolate, methyl B12, AG1, a probiotic, a baby aspirin | Robb Report, February 2024, from his podcast | He asked on his podcast, "Why do people care what supplements I take?" More in our Peter Attia protocol post |
| Jack Dorsey, Twitter and Block cofounder | "The only supplements I take are daily multivitamin and vitamin C, a lot of vitamin C" | CNBC, April 2019, from the Ben Greenfield podcast transcript | He also said he takes Athletic Greens (now AG1) "every now and then" and has not found the discipline to stay on supplements consistently |
| Mark Cuban, investor | Melatonin, vitamin D and vitamin E | Business Insider via AOL, December 2024 | The outlet says he "previously told Business Insider" he takes daily supplements for inflammation and sleep; no doses given |
| Peter Thiel, investor | Human growth hormone daily | Told Bloomberg TV in 2014, reported by Fox News | A prescription hormone. See the risks below |
| Elon Musk | No supplement stack published. Credited "fasting" and "Wegovy" for weight loss in a 2022 reply on Twitter | CU Anschutz, October 2022 | Wegovy is a prescription drug. Covered in longevity drugs |
Look down the middle column and a pattern jumps out. The richest names on the list (Musk, Thiel, Dorsey) say the least about supplements. The longest stacks belong to people whose public brand is health: Johnson, Sinclair, Diamandis, Huberman, Attia. Does that change how much weight you give a 60-pill routine?
A note on commercial ties
Several of the people above sell or partner with supplement brands. Johnson's protocol page lists his own Blueprint products by name. Huberman wrote in his sleep newsletter that "I use supplements from Momentous for all of the above." When the person describing a stack also profits from it, treat their list as one data point and go check the research yourself.
The supplements that show up most often
Count every mention across the table and seven items keep coming back. Here they are, with the evidence and a rough cost if you bought a plain store-brand version. Prices are the list prices shown on Costco's website in October 2026 (as of 2026), divided out per day. Your local price will differ, and any pharmacy or warehouse store brand will be in the same range.
| Supplement | Who in the table takes it | What the evidence says | Rough copy-it cost |
|---|
| Vitamin D | Attia, Sinclair, Cuban | Fixes a deficiency. Did not prevent cancer or heart disease in a 25,871-person trial | About $0.75 a month for 2,000 IU ($14.99 for 600) |
| Omega-3 fish oil | Johnson, Attia (Huberman discusses 1 to 3 g EPA) | No benefit at 1 g a day in healthy people; a 4 g prescription form helped high-risk patients; higher doses raise atrial fibrillation risk | About $3.15 a month for two 1,000 mg softgels ($20.99 for 400) |
| Magnesium | Attia, Huberman, Diamandis | Corrects low intake; sleep evidence is small and low quality | About $3.80 a month ($22.99 for 180) |
| Creatine | Johnson, Diamandis | Strong for strength and muscle with training, including in older adults; brain evidence is early | About $4.90 a month at 5 g a day ($21.99 for 1.48 lb) |
| Multivitamin or greens powder | Dorsey, Huberman, Attia | No mortality benefit in 390,124 adults; the US task force calls the evidence insufficient | About $1.20 a month for a plain multi ($19.99 for 500) |
| Sleep aids (melatonin, theanine, apigenin, glycine) | Cuban, Huberman, Sinclair | Mixed; melatonin labels are often wrong | Varies |
| NMN or other NAD+ boosters | Sinclair, and Diamandis by his "mirror" of Sinclair | Human trials are small and short. Full review in our NMN and NAD+ post | Varies widely |
Seven rows, and five of them cost less than a streaming subscription for the lot. Which of these do you already take without thinking about it?
Vitamin D
Vitamin D is the most common pill among the people above, and Attia's roughly 5,000 IU a day is the highest dose reported. For context, the NIH Office of Dietary Supplements sets the adult recommended intake at 600 IU a day up to age 70 and 800 IU after that, with a tolerable upper limit of 4,000 IU. His dose sits above that upper limit.
The best test of vitamin D for long life is the VITAL trial. It gave 25,871 adults 2,000 IU a day or a placebo for a median of 5.3 years and found no lower rate of invasive cancer or major cardiovascular events. That result fits a simple reading: vitamin D helps people who are low, and adding more to people who already have enough does little for the big diseases.
The copy-it version costs under a dollar a month. The NIH notes that older people and people with dark skin make less vitamin D from sunlight, and that sun through window glass makes none. If either applies to you, or you spend your days indoors, ask your doctor whether to check your level before you pick a dose.
Omega-3 fish oil
Johnson lists an EPA/DHA softgel. Attia takes four high-EPA capsules for about 2 g of EPA a day. On his podcast, Huberman said research supports one to three grams of EPA a day and noted that his guest Dr. Rhonda Patrick takes three to four grams or more.
The trial results split by dose and by who is taking it. In the same VITAL trial, 1 g a day of marine omega-3s did not lower major cardiovascular events or cancer in healthy older adults. In REDUCE-IT, a purified prescription EPA at 4 g a day in patients with heart disease or diabetes and high triglycerides cut the main heart outcome to 17.2% from 22.0%, with more hospital stays for atrial fibrillation in the treated group. A 2021 meta-analysis of 81,210 patients found omega-3 supplements were linked to a 25% higher risk of atrial fibrillation, with the risk greater above 1 g a day.
So the high doses the longevity crowd favours carry a known heart rhythm trade-off. A cheap 1,000 mg store-brand softgel holds 250 mg of EPA plus DHA, so matching Attia's intake with a basic product would take more than a dozen softgels a day. Oily fish is the food route. When did you last have salmon or sardines?
Magnesium
Attia aims for about a gram of elemental magnesium a day across three forms. Huberman takes magnesium threonate before bed. Diamandis takes glycinate and threonate.
The NIH lists the adult recommended intake at 400 to 420 mg for men and 310 to 320 mg for women, and sets the upper limit for magnesium from supplements at 350 mg a day. Many single pills on store shelves hold 400 mg, which is already above that supplement limit. The NIH notes that high doses from supplements can cause diarrhea, nausea and abdominal cramping.
On sleep, a 2021 review of three small trials in 151 older adults found magnesium cut the time to fall asleep by about 17 minutes, but it rated the trials at moderate to high risk of bias with low to very low quality evidence. That is a weak signal. The NIH lists green leafy vegetables, legumes, nuts, seeds and whole grains as good food sources, which you may already be buying.
Creatine
Creatine is the quiet winner of this roundup. Johnson takes 7.5 g a day across two sources. Diamandis takes 5 g. It is also one of the best studied supplements sold.
The International Society of Sports Nutrition reviewed the research and concluded that short and long-term use, up to 30 g a day for 5 years, is safe and well tolerated in healthy people, and that creatine improves high-intensity exercise performance and training gains. For the longevity angle, a meta-analysis of 22 trials in 721 older adults (average ages of 57 to 70 across the studies) found creatine during resistance training added about 1.37 kg more lean mass plus gains in chest and leg press strength compared with training alone.
Note the condition in that sentence: during resistance training. Creatine works with lifting. The brain story is early. A systematic review of six trials in 281 healthy people found possible gains in short-term memory and reasoning, conflicting results elsewhere, and no change in young people.
Plain creatine monohydrate powder at about 16 cents a day is the cheapest serious item on this list. If you already train two or three times a week, this is the one pill with the best case for being worth your money. How many days did you lift last week?
Multivitamin and greens powders
Dorsey keeps it to a multivitamin and vitamin C. Huberman and Attia both take AG1, a greens powder. Attia has disclosed he is an adviser to and investor in the company, according to the Robb Report write-up of his routine.
The evidence here is flat. A 2024 analysis of 390,124 US adults followed for up to 27 years found that multivitamin use was not associated with a mortality benefit. The US Preventive Services Task Force concluded the evidence is insufficient to judge the benefits and harms of multivitamins for preventing heart disease or cancer.
A plain multi may still fill a gap if your diet is narrow, and your doctor can tell you whether yours is. A store-brand bottle works out to about $1.20 a month. A premium greens powder costs many times that, and nothing in the research above shows the extra spend buys a longer life.
Sleep supplements
This is the messiest category. Cuban takes melatonin. Huberman's evening stack is magnesium threonate, theanine and apigenin, sometimes with glycine and GABA. Sinclair takes glycine.
Melatonin has a quality problem before you get to whether it works. A study of 31 products found melatonin content ranged from 83% below to 478% above the label, with some bottles also containing serotonin. For a sleep aid, that range is the difference between nothing and a heavy dose.
The free habits are worth trying first: a fixed wake time, morning light, a cool dark room and no caffeine after lunch. Which of those four would be hardest for you to keep?
NMN and NAD+ boosters
Sinclair takes 1 g of NMN a day according to the Diamandis report, and NMN is the priciest and least proven category in the table. The trials, the FDA history and the monthly cost are in our NMN and NAD+ post.
Billionaire pills with weak or negative evidence
Some items in these stacks have evidence pointing the other way, or almost none at all. Would you keep taking a pill if you knew the best trial found nothing? Talk to your doctor before taking any of the following, and especially before mixing supplements with prescription drugs. Aspirin raises bleeding risk, and the NIH lists statins, steroids, orlistat and thiazide diuretics among the drugs that interact with vitamin D. High doses of anything can cause side effects you would not connect to the pill.
Daily baby aspirin for healthy people. Sinclair and Attia both take one. The US Preventive Services Task Force recommends against starting low-dose aspirin for primary prevention of heart disease in adults 60 or older, and calls it an individual decision with small net benefit for higher-risk adults aged 40 to 59. The trade-off is bleeding risk.
Vitamin E. Cuban takes it. The same task force recommends against using vitamin E or beta carotene supplements to prevent heart disease or cancer. That is one of the few firm "no" grades it gives a vitamin.
Growth hormone for aging. Thiel told Bloomberg TV in 2014 that he takes it daily because it "helps maintain muscle mass." Mayo Clinic says there is little research to suggest HGH can help otherwise healthy adults regain youth and energy, that it may raise the risk of other health conditions, and that experts recommend against using it for aging. In healthy older adults it can add muscle without adding strength.
Megadoses as a default. Attia's 5,000 IU of vitamin D and gram of magnesium both sit above the NIH upper limits. He is a physician. If you copy his doses without a doctor watching your levels, you take on the risk with no one checking.
Long stacks in general. A 60-pill day has never been tested as a whole. Each extra pill adds cost, a chance of an interaction and a chance of a contaminated batch, and the trials above show that even the popular single items often fail to move hard outcomes in healthy people.
Prescription drugs used for longevity. Metformin, Wegovy and the rest are a separate conversation with a doctor. Our longevity drugs post weighs them.
Your own doctor, who knows your history, medications and blood work, is the right person to weigh any of this.
What a billionaire stack costs next to yours
Here is the gap in money terms. The billionaire figures are what they say they take; the copy-it column uses the store-brand prices above.
| Item | Their version | Copy-it version | Monthly cost, copy-it |
|---|
| Vitamin D | Attia: about 5,000 IU | 1,000 to 2,000 IU, or a test first | Under $1 |
| Omega-3 | Attia: high-EPA, about 2 g EPA | Two store-brand softgels, or oily fish | About $3 |
| Magnesium | Attia: three forms, about 1 g | Food first; a pill under 350 mg if your doctor agrees | About $4 or less |
| Creatine | Johnson: 7.5 g | 3 to 5 g monohydrate, only if you lift | About $5 |
| Multivitamin | Huberman and Attia: AG1 | Plain multi if your diet has gaps | About $1.20 |
| Total | 40 to 60+ pills and powders | Four or five items | Roughly $10 to $15 |
Ten to fifteen dollars a month covers the part of the billionaire cabinet with the best evidence. The rest of their spend goes on the experimental tier, testing, and products sold by the people recommending them.
The index fund parallel
The pattern in the table carries over to money. The big, boring basics do most of the work, and the expensive extras add little on average. Plain index funds play the same role in investing that creatine and vitamin D play here; our index investing guide walks through the low-cost version. And if you are working out how much you actually need before you start buying upgrades for your body or your lifestyle, how much money is enough helps you set that figure. What would you do with the $100 or more a month a premium stack would cost?
Your supplement cupboard this week
You do not need a 60-pill routine. Here is a short plan you can start today:
- Look at what you already take. Line up every bottle in your cupboard. Check the dose against the NIH limits above, especially vitamin D (4,000 IU) and supplemental magnesium (350 mg).
- Ask for one blood test, if it makes sense for you. At your next check-up, ask your doctor whether a vitamin D level is worth checking. That one number tells you more than any billionaire's dose.
- Pick at most one new item. If you lift weights, creatine monohydrate has the strongest case. If you never eat fish, ask whether a basic omega-3 makes sense for you.
- Fix sleep for free. Same wake time all seven days, daylight within an hour of waking, no caffeine after noon. Try it for seven nights before buying a sleep supplement.
- Price it. Write down what you spend on supplements a month. If it is more than about $15, ask which items have a trial behind them.
Which of those five could you do before Sunday?
The richest people on this list have access to any pill money can buy. The items they share most often are the cheap ones, and the research backs the cheap ones best.